Monday, March 1, 2010

Low vitamin D levels in children associated with higher plasma glucose and lower HDL

Vitamin D is a steroid hormone and a component of a complex endocrine pathway sometimes called 'vitamin D endocrine system' (Medscape, 2012).  A retrospective record review of pediatric outpatients (age, 2-18 years) included simultaneous measurement of 25-hydroxyvitamin D (25[OH] D) and fasting plasma glucose or 25(OH) D and a lipid panel.

25(OH) D levels were inversely correlated with fasting plasma glucose levels.

Lower 25(OH) D levels were also associated with lower serum high-density lipoprotein cholesterol (HDL) concentrations.

Children who were vitamin D insufficient (25[OH] D ≤30 ng/mL) had higher fasting plasma glucose and lower HDL levels than children who were vitamin D sufficient (25[OH] D >30 ng/mL).

Monounsaturated fats found in vegetable oils, nuts and avocados increase "good" HDL cholesterol levels by 12% http://goo.gl/GBQa5
Image sources: Wikipedia, public domain.

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